Oxygen Saturation Target Range for Extremely Preterm Infants
نویسندگان
چکیده
منابع مشابه
Target ranges of oxygen saturation in extremely preterm infants.
BACKGROUND Previous studies have suggested that the incidence of retinopathy is lower in preterm infants with exposure to reduced levels of oxygenation than in those exposed to higher levels of oxygenation. However, it is unclear what range of oxygen saturation is appropriate to minimize retinopathy without increasing adverse outcomes. METHODS We performed a randomized trial with a 2-by-2 fac...
متن کاملTarget Ranges of Oxygen Saturation in Extremely Preterm Infants
*The authors are listed in the Appendix. The affiliations of the authors and other investigators in the Surfactant, Positive Pressure, and Pulse Oximetry Randomized Trial (SUPPORT) Study Group of the Neonatal Research Network of the Eunice Kennedy Shriver National Institute of Child Health and Human Development are listed in the Appendix. Address reprint requests to Dr. Waldemar A. Carlo at the...
متن کاملOxygen saturation target range for extremely preterm infants: a systematic review and meta-analysis.
IMPORTANCE The optimal oxygen saturation (SpO2) target for extremely preterm infants is unknown. OBJECTIVE To systematically review evidence evaluating the effect of restricted vs liberal oxygen exposure on morbidity and mortality in extremely preterm infants. DATA SOURCES MEDLINE, PubMed, CENTRAL, and CINAHL databases from their inception to March 31, 2014, and abstracts submitted to Pedia...
متن کاملOxygen saturation and outcomes in preterm infants.
BACKGROUND The clinically appropriate range for oxygen saturation in preterm infants is unknown. Previous studies have shown that infants had reduced rates of retinopathy of prematurity when lower targets of oxygen saturation were used. METHODS In three international randomized, controlled trials, we evaluated the effects of targeting an oxygen saturation of 85 to 89%, as compared with a rang...
متن کاملHigher oxygen saturation targets did not improve growth and neurodevelopment in extremely preterm infants.
*Information provided by author. MAIN RESULTS Analysis was by intention to treat. The groups did not differ for growth outcomes or major developmental abnormalities (table), or worst retinopathy (p = 0.34). However, the higher target group had higher rates of dependence on supplemental oxygen at 36 weeks PA (table) and spent more days on oxygen (median 40 v 17.5 d, p,0.001) than those in the st...
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ژورنال
عنوان ژورنال: JAMA Pediatrics
سال: 2015
ISSN: 2168-6203
DOI: 10.1001/jamapediatrics.2014.3307